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has enhanced potency in PIK3CA mutant models through a unique mechanism of action
Product Name Thalidomide-5'-C3-PEG2-OH Synonyms CAS Number n/a Related CAS Molecular Formula C20H24N2O7 Molecular Weight 404
MaP555-Maleimide is a fluorogenic probe
Cy3-CA CAS Number Related CAS Molecular Formula C40H57ClN3O3 Molecular Weight 663
Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Size:10mg has enhanced potency in PIK3CASOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The
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