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Unlike the classic copper-catalyzed azide-alkyne cycloaddition (CuAAC)
295 SMILES OC(=O)CCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
FPFT-2216 is a molecular glue compound
Product Name tert-butyl N-{2-[2-(piperazin-1-yl)ethoxy]ethyl}carbamate Synonyms CAS Number n/a Related CAS Molecular Formula C13H27N3O3 Molecular Weight 273
Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Unlike the classic copper-catalyzed azide-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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