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Product Name Thalidomide-O-acetamido-C6-amine HCl Synonyms Thalidomide-4'-O-acetamido-C6-amine HCl CAS Number 2376990-31-5 Related CAS 1950635-13-8 (free base)
Contains an E3 ligase ligand substituted with piperazine
Coumarin (353Ex/434Em) has moderate to high quantum yields and extinction coefficients
making it ideal for aqueous-based applications without requiring organic solvents
Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE amine-acid Product Name Thalidomide-O-acetamido-C6-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The
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