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Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Size:25mg 351 SMILES CC(C)(C)OC(=O)CN1CCN(CCN)CC1 Purity (HPLC)

SKU 90147528880
4.2
USD445.00 USD483.00

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Description

351 SMILES CC(C)(C)OC(=O)CN1CCN(CCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

46 SMILES OCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

and strong selectivity for SARM1 over other NADases

251 Purity (HPLC) >= 95% Solubility DMSO

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-PNP Size:25mg 351 SMILES CC(C)(C)OC(=O)CN1CCN(CCN)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP

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