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Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE ca 6 Purity (HPLC) >= 95%

SKU 82281863698
4.7
EUR495.00 EUR515.00

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Description

6 Purity (HPLC) >= 95% Solubility DMSO

and drug development

S)-AHPC-CO-PEG5-C2-amine HCl Synonyms CAS Number 2375432-97-4 Related CAS Molecular Formula C35H56ClN5O9S Molecular Weight 758

DOTA bifucational chelator containing an amine-reactive NHS group

Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE ca 6 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl

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