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308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name 1-bromo-2-(methoxy-d3)benzene Synonyms 1-bromo-2-(²H3)methoxybenzene CAS Number 892397-56-7 Related CAS Molecular Formula C7H7BrO Molecular Weight 190
The water-soluble PEG3 spacer should minimize the interaction between the dye and the biomolecule to be labeled
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide
DBCO-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:1mg 308 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=CC(OCCC#C)=CC=C12 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
