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This ADC building block is widely used in the synthesis of antibody-drug conjugates for cancer research
946 SMILES OC1=C(Br)C=C(\C=C2/C(=O)NC3=C2C=C(I)C=C3)C=C1Br Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
bioconjchem
Product Name DOTA-tris(t-Bu)ester-NHS Synonyms CAS Number 819869-77-7 Related CAS Molecular Formula C32H55N5O10 Molecular Weight 669
DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP biotin This ADC building block isSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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