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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan fmoc It forms a covalent bond

Description

It forms a covalent bond with the SNAP-tag protein

823 Purity (HPLC) >= 95% Solubility DMSO

542 Purity (HPLC) >= 95% Solubility DMSO

propargylamide CAS Number: N/A Molecular Formula: C28H25N3O4 Molecular Weight: 467

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan fmoc It forms a covalent bondSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage

Exchange/Return Notes