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Product Name CRBN5-CLIP-0C-PIP Synonyms CAS Number N/A Related CAS N/A Molecular Formula C31H31N7O6 Molecular Weight 597
S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number 2341796-75-4 Related CAS 2341796-74-3 (free base) Molecular Formula C33H53Cl2N5O4S Molecular Weight 686
S)-AHPC-CO-PEG1-C2-acid Synonyms CAS Number 2172820-07-2 Related CAS Molecular Formula C28H38N4O7S Molecular Weight 574
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bc Product Name CRBN5-CLIP-0C-PIP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous
