Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE ala Product Name CRBN5-CLIP-0C-PIP Synonyms CAS

Product Name CRBN5-CLIP-0C-PIP Synonyms CAS Number N/A Related CAS N/A Molecular Formula C31H31N7O6 Molecular Weight 597

Product Name Phthalimidinoglutarimide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C17H22ClN3O3 Molecular Weight 351

406 SMILES [N-]=[N+]=NCCCCCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Fmoc-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C43H58N6O11 Molecular Weight 834

Propargyl-Acetyl-Val-Cit-PAB(m-PEG8)-MMAE ala Product Name CRBN5-CLIP-0C-PIP Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing