DOTA-PEG5-C2-amine piperazine NRX-1532 acts as molecular glue

NRX-1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid Synonyms Intermediate for Venetoclax

334 SMILES O=C1N(C2CCC(=O)NC2=O)C(=O)C2=C(OCCOCC#C)C=CC=C12 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

DOTA-PEG5-C2-amine piperazine NRX-1532 acts as molecular glueDOTA bifucational chelator containing an amine group, a PEG linker, and the macrocyclic chelator DOTA ( 1,4,7,10 tetraazacyclododecane 1,4,7,10 tetraacetic acid). It can be used in many different diagnostic and therapeutic applications, such as MRI contrast agents, PET and SPECT imaging agents, and radiotherapeutic agents. Product Name DOTA PEG5 C2 amine Synonyms CAS Number n a Related CAS Molecular Formula C28H54N6O12 Molecular Weight 666. 77 SMILES