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42 SMILES Cl
75 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCOCCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
S)-AHPC-CO-C9-NH2 HCl Synonyms CAS Number 2349429-71-4 Related CAS Molecular Formula C32H50ClN5O4S Molecular Weight 636
Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C85H105FN10O21 Molecular Weight 1621
Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:1mg 42 SMILES ClSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent
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