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Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-Exatecan Size:1mg Product Name Thalidomide-5'-piperazine-C2-OH Synonyms CAS

SKU 75998549421
4.6
EUR445.00 EUR493.00

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Description

Product Name Thalidomide-5'-piperazine-C2-OH Synonyms CAS Number 2222115-00-4 Related CAS Molecular Formula C19H22N4O5 Molecular Weight 386

62 SMILES Cl

Product Name Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C89H145N13O28 Molecular Weight 1845

09 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-Exatecan Size:1mg Product Name Thalidomide-5'-piperazine-C2-OH Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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