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Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyne CAS Number 2408797-68-0 Related CAS Molecular Formula C18H15N3O5 Molecular Weight 353
specifically used in the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction
CP-Tetrazine is a SNAP-tag substrate containg a methayltetrazine group for click chemistry applications
S)-AHPC-CO-C5-piperazine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C32H50Cl2N6O4S Molecular Weight 685
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan acid-acid Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyneSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
