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DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:25mg 458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC)

SKU 6612447565
4.3
EUR495.00 EUR544.00

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Description

458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

935 Purity (HPLC) >= 95% Solubility DMSO

The TMP-tag is based on the tight binding between trimethoprim (TMP)

DiAc-6-FAM-DBCO can be used for fluorescent labeling through copper-free click chemistry reaction with azides (494Ex/526Em after hydrolysis)

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:25mg 458 SMILES CC(C)(C)OC(=O)CN1CCN(CCN2CCNCC2)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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