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Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde 89 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)

SKU 64858947727
4.2
USD445.00 USD491.00

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Description

89 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Lenalidomide-CO-PEG2-Cl Synonyms Lenalidomide-4'-CO-PEG2-Cl CAS Number n/a Related CAS Molecular Formula C20H24ClN3O6 Molecular Weight 437

354 SMILES OCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan deuterium-labeled-aldehyde 89 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCCCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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