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Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester 214 Purity (HPLC) >= 95%

SKU 59504262622
4.2
EUR445.00 EUR470.00

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Description

214 Purity (HPLC) >= 95% Solubility DMSO

BG-Biotin can be used for protein biotinylation

Product Name: 5(6)-FAM PEG3 azide Synonyms: 5-(and 6)-Carboxyfluorescein-PEG3-Azide CAS Number: N/A Molecular Formula: C29H28N4O9 Molecular Weight: 576

Product Name: Lissamine rhodamine B C2 maleimide Synonyms: Sulforhodamine B C2 maleimide CAS Number: 1800246-48-3 Molecular Formula: C33H36N4O8S2 Molecular Weight: 680

Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan deuterium-labeled-carboxylic ester 214 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker

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