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Product Name CR8 Synonyms CAS Number 294646-77-8 Related CAS Molecular Formula C25H30N6O Molecular Weight 430
Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C59H95N11O23 Molecular Weight 1326
Caprioglio
84 SMILES Cl
Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan chemical Product Name CR8 Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,
