DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker 419 SMILES OCCOCCOCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

419 SMILES OCCOCCOCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CDg18 is the first M2 macrophage selective fluorescent probe

Product Name Thalidomide-O-acetamido-propargyl Synonyms Thalidomide-4'-O-acetamido-propargyl CAS Number n/a Related CAS Molecular Formula C18H15N3O6 Molecular Weight 369

The payload is monomethyl auristatin E (MMAE)

DBCO-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-PNP linker 419 SMILES OCCOCCOCCCC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further