Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg 389 SMILES CC(C)(C)OC(=O)N1CCN(CC1)C1CCNCC1 Purity (HPLC)

389 SMILES CC(C)(C)OC(=O)N1CCN(CC1)C1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Contains Cy3 fluorophore

Protein degrader building block

and strong selectivity for SARM1 over other NADases

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP Size:25mg 389 SMILES CC(C)(C)OC(=O)N1CCN(CC1)C1CCNCC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous