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Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:50mg Product Name MaP555-Azide Synonyms CAS

SKU 50770005380
4.4
USD195.00 USD219.00

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Description

Product Name MaP555-Azide Synonyms CAS Number n/a Related CAS Molecular Formula C28H30N8O5S Molecular Weight 590

Degrader building block for targeted protein degradation

418 SMILES OCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

This two-step mechanism provides high specificity and sensitivity

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:50mg Product Name MaP555-Azide Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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