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Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg 489 SMILES OCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)

SKU 50659747579
4.3
USD495.00 USD519.00

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Description

489 SMILES OCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB Synonyms CAS Number Related CAS Molecular Formula C38H59N7O12 Molecular Weight 805

Product Name Phthalimidinoglutarimide-5'-C3-amine HCl Synonyms CAS Number n/a Related CAS 2589697-97-0 (free base) Molecular Formula C16H20ClN3O3 Molecular Weight 337

Thalidomide is an immunomodulatory compound with diverse biological activities

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:5mg 489 SMILES OCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous

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