Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Sulforhodamine B Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate Synonyms

Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate Synonyms CAS Number 688020-38-4 Related CAS Molecular Formula C15H29N3O2 Molecular Weight 283

Product Name Phthalimidinoglutarimide-C7-Br Synonyms Phthalimidinoglutarimide-4'-C7-Br CAS Number n/a Related CAS Molecular Formula C20H25BrN2O3 Molecular Weight 421

Product Name Thalidomide-O-acetamido-PEG5-C2-amine HCl Synonyms Thalidomide-4'-O-acetamido-PEG5-C2-amine HCl CAS Number n/a Related CAS 1957236-24-6 (free base) Molecular Formula C27H39ClN4O11 Molecular Weight 631

Product Name Thalidomide-5'-O-PEG6-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C28H36N2O11 Molecular Weight 576

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE Sulforhodamine B Product Name tert-butyl 2-[4-(piperidin-4-yl)piperazin-1-yl]acetate SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate