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making the linkers highly adaptable for diverse ADC and related applications
Product Name Pomalidomide-PEG2-C2-acid Synonyms Pomalidomide-4'-PEG2-C2-acid CAS Number 2140807-17-4 Related CAS Molecular Formula C20H23N3O8 Molecular Weight 433
334 SMILES O=C(CCC#C)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
It induces degradation of SALL4 (ZF2)
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4) tamra making the linkers highly adaptableSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX
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