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DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg 507 SMILES [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCOCC3)C=C2)C1=O Purity (HPLC)

SKU 46477874547
4.6
USD445.00 USD476.00

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Description

507 SMILES [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCOCC3)C=C2)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

It is based on a proximity-induced covalent Michael addition between an engineered cysteine (Cys) residue in Escherichia coli dihydrofolate reductase (eDHFR) and optimized trimethoprim (TMP)-acrylamide conjugates with minimal linker lengths

Product Name Pomalidomide-5'-PEG6-OH Synonyms CAS Number 2641838-86-8 Related CAS Molecular Formula C25H35N3O10 Molecular Weight 537

6-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Size:100mg 507 SMILES [H][C@@]1(CCC(=O)NC1=O)N1CC2=C(C=CC=C2OCC2=CC=C(CN3CCOCC3)C=C2)C1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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