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SOLU-KNEX® cleavable linker features a Val-Cit dipeptide
propargylamide CAS Number: 510758-19-7 Molecular Formula: C24H15NO6 Molecular Weight: 413
such as genome duplication and chromatin maintenance
Product Name Thalidomide-O-acetamido-PEG3-OH Synonyms Thalidomide-4'-O-acetamido-PEG3-OH CAS Number n/a Related CAS Molecular Formula C21H25N3O9 Molecular Weight 463
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-MMAE Size:5mg SOLU-KNEX® cleavable linker features aSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly
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