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amine-containing groups
17515–17523
Product Name Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C54H79N7O22 Molecular Weight 1178
794 Purity (HPLC) >= 95% Solubility DMSO
Mal-Acetyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-MMAE Size:5mg amine-containing groupsSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate
