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MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg 408 SMILES OCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)

SKU 39742308020
4.5
USD495.00 USD545.00

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Description

408 SMILES OCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCCCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

754 SMILES OCCOCCOCCOCCOCCOCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Phthalimidinoglutarimide-propargyl-PEG1-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG1-OH CAS Number n/a Related CAS Molecular Formula C18H18N2O5 Molecular Weight 342

MC-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg 408 SMILES OCCN1CCN(CC1)C1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate

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