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OSu-Glu-VC-PAB-MMAE Size:1mg 925 Purity (HPLC) >= 95%

SKU 39237144606
4.2
EUR200.00 EUR228.00

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Ships within 48 hours · Estimated delivery Aug 20 - Aug 25

Description

925 Purity (HPLC) >= 95% Solubility DMSO

Product Name Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C54H80N8O20 Molecular Weight 1161

It binds to the VHL E3 ligase with an IC50 of 0

PET and SPECT imaging agents

OSu-Glu-VC-PAB-MMAE Size:1mg 925 Purity (HPLC) >= 95%SuO Glu Val Cit PAB MMAE (NHS Glutarate Val Cit PAB MMAE) is a cleavable ADC linkerpayload system consisting of a SuO Glu Val Cit PAB peptide linker and the microtubule disrupting cytotoxic payload MMAE. This ADC building block is widely used in the synthesis of antibody drug conjugates for cancer research, where the Val Cit PAB motif enables enzyme cleavable release of MMAE inside target cells, supporting highly potent, targeted delivery in

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