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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE deuterium-labeled-heterocycle 1004359-67-4 Molecular Formula C38H34N8O5 Molecular

SKU 36236058285
4.5
USD495.00 USD520.00

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Description

1004359-67-4 Molecular Formula C38H34N8O5 Molecular Weight 682

915 Purity (HPLC) >= 95% Solubility DMSO

657 Purity (HPLC) >= 95% Solubility DMSO

21 Purity (HPLC) >= 95% Solubility DMSO

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE deuterium-labeled-heterocycle 1004359-67-4 Molecular Formula C38H34N8O5 MolecularSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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