CRBN5-SNAP2-0C-PIP Size:100nmol The taselisib-induced degradation of mutant

The taselisib-induced degradation of mutant p110a protein is ubiquitin-mediated and proteasome-dependent

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where copper can be toxic or interfere with biological processes

54 Purity (HPLC) >= 95% Solubility DMSO

CRBN5-SNAP2-0C-PIP Size:100nmol The taselisib-induced degradation of mutantCRBN5 SNAP2 0C PIP is a SNAP PROteolysis TArgeting Chimera (SNAP PROTAC), which recruit the VHL or CRBN ubiquitin E3 ligases to induce the degradation of SNAP fusion proteins. Endogenous tagging enabled the visualization and the selective depletion of a SNAP clathrin light chain fusion protein using SNAP PROTACs. The addition of PROTACs to the SNAP tag reagent toolbox facilitates the comprehensive analysis of protein function with a single gene