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535-542 Donovan
Tunnermann
This is a big advantage in living systems
Journal of Hematology & Oncology 2021
DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB-PNP Size:100mg 535-542 DonovanSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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