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Product Name Thalidomide-O-C4-amine HCl Synonyms Thalidomide-4'-O-C4-amine HCl CAS Number 2376990-29-1 Related CAS Molecular Formula C17H20ClN3O5 Molecular Weight 381
188 Purity (HPLC) >= 95% Solubility DMSO
376 SMILES OC(=O)C1CCN(CC1)C1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
6-tetrahydro-[1
DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan amine-acid Product Name Thalidomide-O-C4-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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