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DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc & Rentmeister

SKU 29191221179
4.8
USD495.00 USD524.00

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Ships within 48 hours · Estimated delivery Aug 23 - Aug 28

Description

& Rentmeister

Product Name Pomalidomide-CO-C2-acid Synonyms Pomalidomide-4'-CO-C2-acid CAS Number 2417174-32-2 Related CAS Molecular Formula C17H15N3O7 Molecular Weight 373

446 SMILES CC(C)(C)OC(=O)NCCN1CCN(CCOCCN)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

[O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=[OH+])NCCN1C(=O)C=CC1=O Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE adc & RentmeisterSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to

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