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Abstract S6-04: The PI3K inhibitor
968 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid CAS Number 2488752-64-1 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434
61 SMILES [2H]C([2H])([2H])NC1=C(Cl)C=C(F)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-PEG2-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Size:25mg Abstract S6-04: The PI3K inhibitorSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a
