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Product Name Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C64H80FN9O19 Molecular Weight 1298
579 SMILES O=C1N(CC2=C(NCCOCCOCCOCCOCCOCC#C)C=CC=C12)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Product Name BODIPY labeled DCAF1 Binder Synonyms CAS Number n/a Related CAS Molecular Formula C39H43BClF5N8O3 Molecular Weight 813
NCCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg Product Name Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG4)-Exatecan Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
