Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Pomalidomide-CO-C3-alkyne Synonyms Pomalidomide-4'-CO-C3-alkyne

Product Name Pomalidomide-CO-C3-alkyne Synonyms Pomalidomide-4'-CO-C3-alkyne CAS Number n/a Related CAS Molecular Formula C19H17N3O5 Molecular Weight 367

707 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C95H141N11O23 Molecular Weight 1805

Product Name Thalidomide-O-PEG2-C2-acid Synonyms Thalidomide-4'-O-PEG2-C2-acid CAS Number 2488752-64-1 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Pomalidomide-CO-C3-alkyne Synonyms Pomalidomide-4'-CO-C3-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I