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Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8) Size:10mg This structure allows DOTA to

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Description

This structure allows DOTA to form highly stable complexes with a variety of metal cations

519 Purity (HPLC) >= 95% Solubility DMSO

69 Purity (HPLC) >= 95% Solubility DMSO

71 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCO)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8) Size:10mg This structure allows DOTA toSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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