DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)

384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Azide-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C44H76N10O15 Molecular Weight 985

S)-AHPC-CO-PEG4-C2-acid Synonyms CAS Number 2172820-12-9 Related CAS Molecular Formula C34H50N4O10S Molecular Weight 706

Product Name: Lissamine rhodamine B C2 maleimide Synonyms: Sulforhodamine B C2 maleimide CAS Number: 1800246-48-3 Molecular Formula: C33H36N4O8S2 Molecular Weight: 680

DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg 384 SMILES OCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC