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Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg 823 Purity (HPLC) >= 95%

SKU 21288623522
4.3
USD445.00 USD480.00

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Description

823 Purity (HPLC) >= 95% Solubility DMSO

Product Name Phthalimidinoglutarimide-propargyl-PEG5-OH Synonyms Phthalimidinoglutarimide-4'-propargyl-PEG5-OH CAS Number n/a Related CAS Molecular Formula C26H34N2O9 Molecular Weight 518

Product Name Pomalidomide-5'-C6-amine HCl Synonyms CAS Number n/a Related CAS 2097509-16-3 (free base) Molecular Formula C19H25ClN4O4 Molecular Weight 408

Product Name Thalidomide-O-acetamido-PEG3-OH Synonyms Thalidomide-4'-O-acetamido-PEG3-OH CAS Number n/a Related CAS Molecular Formula C21H25N3O9 Molecular Weight 463

Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg 823 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a

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