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Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg 69 SMILES Cl

SKU 2022111908
4.7
USD495.00 USD537.00

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Description

69 SMILES Cl

Product Name Lenalidomide-acetamido-O-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-C2-Cl CAS Number n/a Related CAS Molecular Formula C17H18ClN3O5 Molecular Weight 379

11 Purity (HPLC) >= 95% Solubility DMSO

TMR dye (555Ex/585Em) provides strong red fluorescence

Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Size:10mg 69 SMILES ClSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to

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