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MaP555-Alkyne is is a fluorogenic probe
Identification of Potent
562 SMILES OC1=CC2=C(C=C1)C1(OC(=O)C3=CC=C(C=C13)C(=O)NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(O)C=C1O2 Purity (HPLC) 98% Shipping Conditions Room Temperature Storage Conditions Refrigerated Regulatory Statemen: For Research Use Only
CA-N3 is a HaloTag ligand containing an azide functional group
Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-Exatecan Size:10mg MaP555-Alkyne is is a fluorogenicSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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