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Product Name DOTA-C2-DBCO Synonyms CAS Number 1374865-01-6 Related CAS Molecular Formula C34H42N6O8 Molecular Weight 662
Cy3 maleimide
MaP555 mainly exists in the fluorescent zwitterion form
Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C87H140N14O26 Molecular Weight 1798
Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-Exatecan carboxylic acid Product Name DOTA-C2-DBCO Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
