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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE building block 8 SMILES Cl

SKU 1612330123
4.1
USD495.00 USD518.00

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Ships within 48 hours · Estimated delivery Aug 14 - Aug 19

Description

8 SMILES Cl

Product Name DOTA-tris(t-Bu)ester-PEG5-C2-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C47H83N7O15 Molecular Weight 986

47 Purity (HPLC) >= 95% Physical Appearance Light Yellow Solid Optical Properties n/a Solubility DMSO

This dye hass bright fluorescence

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-MMAE building block 8 SMILES ClSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is monomethyl

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