Trametiglue Size:2mg CC-92480 promotes rapid and extensive

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

Product Name Thalidomide-5'-O-C1-acid Synonyms CAS Number 2467425-53-0 Related CAS Molecular Formula C15H12N2O7 Molecular Weight 332

379 SMILES OCCCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

357 SMILES OCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Trametiglue Size:2mg CC-92480 promotes rapid and extensiveTrametiglue acts as molecular glue. Trametiglue combines the potency and off rate kinetics of trametinib on KSR bound MEK with the functional ability of CH5126766 to promote, and potentially trap, inactive states of RAF bound MEK. Product Name Trametiglue Synonyms CAS Number 2666940 97 0 Related CAS Molecular Formula C25H24FIN6O5S Molecular Weight 666. 47 SMILES CNS(=O)(=O)NC1=CC=CC(=C1)N1C(=O)N(C2CC2)C(=O)C2=C(NC3=C(F)C=C(I)C=C3)N(C)C(=O)C(C)=C12