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127 Purity (HPLC) >= 95% Solubility DMSO
CPY dye (short for carbopyronine
It functions through SARM1’s base-exchange reaction
Product Name Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB Synonyms CAS Number Related CAS Molecular Formula C38H55N9O11 Molecular Weight 813
Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan Size:5mg 127 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker
