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Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr Product Name NDB-TM Synonyms CAS

SKU 12194433127
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Description

Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266

Oregon Green resists fading under prolonged illumination better than fluorescein

Product Name Indisulam Synonyms CAS Number 165668-41-7 Related CAS Molecular Formula C14H12ClN3O4S2 Molecular Weight 385

268 SMILES OC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan tmr Product Name NDB-TM Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I

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