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Three shared GO functions are identified across all diseased states, including RNA polymerase II transcription factory activity, ligand-activated sequence-specific DNA binding, PDZ domain binding, and flavin adenine dinucleotide binding. Interestingly, the GO MF terms protein binding or identical protein binding were significantly represented in both sets of upregulated and downregulated genes across all disease states, highlighting the fundamental roles of protein interactions in the molecular pathology of CD, UC, and SI-NET

We also cast these lures in 10 feet of water or less and work them as a jerk bait